孫仲銘

Copper-Catalyzed Regioselective Annulation of Pyrazolamine with 3-Methylpyrrolone

應用化學系分子科學

銅催化、氧化偶聯、雙鍵轉換、自由基機構、區域選擇性、含氮雜環、copper catalysis、oxidative annulation、alkene isomerization、radical mechanism、regioselectivity、N-heterocycles

Metal-Base Mediated Multicomponent Reaction for the Synthesis of Biologically Interesting Novel 3H-pyrrol-3-one and 4H-Imidazole-4-one derivatives

永續化學科技國際研究生博士學位學程

多組分反應、3H-吡咯-3-酮、咪唑-4(2H)-酮、1-氮二烯、炔丙胺前体、分子內環化反應、Multicomponent Reaction、3H-pyrrol-3-one、Imidazole-4-(2H)-ones、1-Azadienes、Propargylamine precursor、InIntramolecular cyclization.

Rhodium (III)-Catalyzed (4+2) Regioselective Annulation of 2-Benzyl-2H-indazole-6-carboxylic Acid with Iodonium Ylides/A Direct Synthesis of Substituted Exocyclic 1H-Pyrrol-3(2H)-Ones by Base-Mediated Multicomponent [3+2] Cycloaddition Reaction

應用化學系

銠金屬、吲唑、位置選擇性、碘偶極體、羧酸、Rhodium (III)-Catalyzed、indazole、Regioselective、Iodonium Ylides、carboxylic Acid

(1) A Novel Approach for the Synthesis of Indole-Fused Benzodiazepines and Cinnoline-Fused Pyrazoles via Pd(II)-Catalyzed Cycloaddition with Allenoates (2) Utilizing Alkyne Esters/Amides for Unconventional Rh(III)-Catalyzed Cycloaddition and Electrosynthesis of Biologically Active Heterocycles

應用化學系

環加成反應、丙二烯酯、C−H 活化、螺旋掌性中心、炔酸酯、綠色化學、Cycloaddition、Allenoates、C−H activation、Spiral chiral center、Alkyne Esters、Green Chemistry

Substrate-Controlled Rh (III)-Catalyzed Regiodivergent Annulation towards Fused and Spiro Benzimidazoles./ Rapid Synthesis of Benzimidazole-Fused Isoindoles by Rh(III)-Catalyzed (4+1) Cascade C-H/ N-H Annulation of 2-Arylbenzimidazoles with Alkynoates./ Rh (III)-Catalyzed [4+2] C-H Annulation of Pyrazolone with Diazo compounds.

應用化學系碩博士班

銠金屬催化碳氫鍵活化、2-芳基苯並咪唑、順丁烯二醯亞胺、重氮化合物、吡唑啉酮、螺環稠環化合物、Rhodium-catalyzed C-H bond activation、2-arylbenzimidazole、maleimide、diazo compound、pyrazolone、spiro-/ fused-compound

Synthesis of isoquinoline-concentrated isoquinolines by intramolecular hydrogenation/ Aza-Claisen type rearrangement cascade reaction/Rhodium metal-catalyzed synthesis of [4 + 2] cyclized cinnoline derivatives from N-aryl pyrazolinones with diazo/Palladium-catalyzed [5 + 2] cyclization of tryptophan methyl ester with alkynate

應用化學系碩博士班

金屬催化、碳-氫鍵活化、環化加成反應、異喹啉、噌啉、七元環氮雜吲哚、metal catalysis、C-H bond activation、cycloaddition reaction、isoquinoline、cinnoline、heptadeca-azaindole

1.Rhodium-Catalyzed [4+2] Annulation of N-aryl Pyrazolones with Diazos to access Pyrazolone-Fused Cinnolines2.Rh(III)-Catalyzed Switchable [4 + 1] and [4 + 2] Annulation of N-aryl pyrazolones with maleimides: A Facile Access to Spiro Pyrazoline Pyrrolidines and Fused Pyrazolopyrrolo Cinnolines3.New drug development of simvastatin for the treatment of Left ventricular noncompaction

應用化學系分子科學碩博士班

銠金屬催化碳氫鍵活化、吡唑啉酮、重氮化合物、噌啉類衍生物、馬來醯亞胺、螺環稠環化合物、辛伐他汀、C-H activation by rhodium(III)-catalyzed、pyrazolone、diazo compounds、cinnoline、maleimide、spiro/fused compounds

(1)Substrate-Controlled Rh(III)-Catalyzed Regiodivergent (4+2)/(4+1) Annulation of 2-Arylbenzimidazole with Maleimides toward Fused and Spiro Benzimidazoles(2)Rh(III)-Catalyzed [4+2] C-H Annulation of 2-Arylbenzimidazole with Cyclic Diazo Compound(3)Rh(III)-Catalyzed C-H Annulation of 2-Arylbenzimidazole and Element Sulfur

應用化學系碩博士班

銠金屬催化碳氫鍵活化、2-芳基苯並咪唑、N-取代順丁烯二醯亞胺、環狀重氮化合物、硫粉、rhodium-catalyzed C-H bond activation、2-arylbenzimidazole、N-substituted maleimide、cyclic diazo compound、elemental sulfur

Molecular Iodine Promoted [3+2] Oxidative Cyclization for the Synthesis of Heteroarenes-Fused [1,2,4]- Thiadiazole/Selenadiazole / Gold assisted Synthesis of Isoquinolino[1,2-a]isoquinoline Derivatives

應用化學系碩博士班

噻二唑、硒二唑、異喹啉、Thiadiazole、Selenadiazole、isoquinoline

Rapid Synthesis of Hexahydropyrrolo[3,4-b]pyrrole-Fused Quinolines via A Consecutive [3+2] Cycloaddition and Reduction/Intramolecular Lactamization Cascade Diastereospecific Synthesis of tetrahydroisoquinolines via Radical Cyclization: An Application in the Synthesis of epi-Tadalafil

應用化學系碩博士班

[3 + 2] 環化加成反應、偶氮甲鹼偶極體、分子內內醯胺化、轉醯胺反應、非鏡像專一性的合成、異喹啉、[3 + 2] cycloaddition reaction、azomethine ylides、intramolecular lactamization、transamidation reaction、diastereospecific synthesis、isoquinolines

(I) Multicomponent Reaction Synthesis of Thiazolidine-Linked Benzimidazole Derivatives (II) Synthesis of Tetrahydroisoquinoline Heterocyclic Small Molecule Derivatives via Radical Pictet-Spengler Reaction

應用化學系碩博士班

多分子反應、噻唑烷、苯并咪唑、自由基皮克特－施彭格勒、四氫異喹啉、Multicomponent Reactio、Thiazolidine、Benzimidazole、Tetrahydroisoquinoline、Radical Pictet-Spengler Reaction

(1)Catalyst-Controlled Chemodivergent Annulation to Indolo/Pyrrolo- Fused Diazepine and Quinoxaline(2)Metal-catalyzed regioselective synthesis of isoquino [1,2-a] isoquinolines via Aza-Claisen type rearrangement(3)Synthesis of Tetrahydroisoquinoline Heterocyclic Small Molecule Derivatives via Radical Pictet-Spengler Reaction

應用化學系碩博士班

二氮雜草、喹喔啉、金屬催化、四氫異喹啉、Diazepine、Quinoxaline、Metal-catalyzed、Tetrahydroisoquinoline

Design and Synthesis of Biologically Interesting Novel Fused/Linked Heterocycles

應用化學系碩博士班

稠合/連接的雜環、diazepino [1、7-a]吲哚、indolo [1、2-a]喹喔啉、benzoimidazo [2、1-α]異喹啉、角isocoumarinoselenazoles、fused/linked heterocycles、7-a]indole、2-a]quinoxaline、benzoimidazo[2、1-a]isoquinolines、angular isocoumarinoselenazoles、benzoimidazothiazetidine、benzoimidazothiadiazine

One-Pot, Three-Component Regioselective Synthesis of 2-Iminothiazole and 2-Thiohydantoin and One-pot Synthesis of 5-Imino-1, 2, 4-Thiadiazole with Iodine as S-N Bond Forming Reagent

應用化學系碩博士班

一鍋化、三種化合物、區域選擇性、2-亞胺基噻唑、2-硫代乙內醯脲、碘、硫-氮鍵生成、5-亞胺基-1、2、4-噻二唑、One-Pot、Three-Component、Regioselective、2-Iminothiazole、2-Thiohydantoin、Iodine、S-N Bond Forming、5-Imino-1、4-Thiadiazole

Catalyst-Controlled Selective 7-exo-dig and 8-endo-dig Cyclization of Triazol-1-ylbenzamide for the Synthesis of Benzotriazolodiazepin-6-ones and Benzotriazolodiazocin-7-ones

應用化學系碩博士班

環內二角、環外二角、催化、鈀、銀、triazole、benzamide、endo、exo、dig

(I) Synthesis of Thio(seleno)hydantoin-fused tetrahydroisoquinolines and diketopiperazine-fused tetrahydroisoquinolines (II) One-pot Synthesis of Chiral 2-imino thia(selena)zole derivatives and 2-thio(seleno)xoimidazolin-4-ones

應用化學系碩博士班

四氫異喹啉衍生物、雜環小分子、Thio(seleno)hydantoin-fused tetrahydroisoquinolines、Chiral 2-imino thia(selena)zole derivatives、Diketopiperazine-fused tetrahydroisoquinolines、2-Thio(seleno)xoimidazolin-4-ones

Design and Synthesis of Indole-Fused Diazocine, Diazepine and Triazole Fused-Benzoxazocinones of Biological Interest

應用化學系碩博士班

吲哚并二氮芳辛、二氮呯、[5+2]成環反應、三唑并1、5-Benzoxazocinone、乙內醯脲并四氫氧基氮雜卓吲哚、串聯反應、Indole Fused Diazocine、Diazepine、[5+2] Annulation、Triazole Fused-1、5-Benzoxazocinones、Hydantoin-Fused Tetrahydroazepino Indoles、Cascade Reaction

(I) Synthesis of benzimidazole linked indoline derivative by acid catalyst(II) One-pot synthesis of derivative of ellipticine which has the activity against Mycobacterium tuberculosis

應用化學系碩博士班

苯并咪唑、吲哚啉、橢圓玫瑰樹鹼、抗結核菌、benzimidazole、indoline、ellipticine、anti-TB

1.Diversity-Oriented Synthesis of Coumarin-Linked Benzimidazoles via a One-Pot, Three-Step, Intramolecular Knoevenagal Cyclization 2.Multicomponent Reaction Synthesis of 2-aza-7-arylpyrrolizidine alkaloid Derivatives

應用化學系碩博士班

克腦文蓋爾環化、香豆素、苯並咪唑、多分子反應、吡咯烷啶、生物鹼、Knoevenagal Cyclization、Coumarin、Benzimidazole、Multicomponent Reaction、pyrrolizidine、alkaloid

Design, Synthesis and Diversification of Poly-heterocyclic and Organophosphorus Compounds

應用化學系碩博士班

吲哚生物鹼、烏吉去保護/合環反應、微波輔助反應、多重成分反應、位置選擇性合成、有機磷化學、Indole alkaloids、Ugi/Deprotection/Cyclization、Miicrowave assisted reaction、Multicomponent reaction、Regioselective synthesis、Organophosphorus compounds

Synthesis of Tetrahydroisoquinoline Derivatives Molecular Library and Gold-Assisted Synthesis of Isoquinolino[1,2-a]isoquinoline Derivatives

應用化學系碩博士班

四氫異喹啉、皮克特－施彭格勒反應、金催化、tetrahydroisoquinoline、Pictet-Spengler reaction、gold catalyze

(I) The Design and Synthesis of Benzimidazole and Dihydroquinazolines Derivatives Based on Lead Compound (II) Ruthenium-Catalysed C-H activation to the Synthesis of [4,5]imidazo[2,1-a]isoindole Derivatives

應用化學系碩博士班

精神分裂症、碳氫活化反應、釕金屬催化、胺基酸氧化酶抑制劑、RS-D7、ruthenium、C-H bond、DAOI

1. Design and Synthesis of D-amino Oxidase Inhibitor for Schizophrenia Treatment 2. Microwave Enhanced, One-Pot Synthesis of Benzazoles and Quinazolinones via Iron Pentacarbonyl Mediated Carbonylation of Aryl Iodides

應用化學系碩博士班

D-胺基酸氧化酶抑制劑、精神分裂症、喹唑啉酮、苯並咪唑、一鍋化合成、五羰基鐵、微波、Schizophrenia、D-amino oxidase、quinazolinones、Benzimidazole、Fe(CO)5、microwave irradiation、one-pot synthesis

Copper-Catalysed Aerobic Oxidative Carbocyclization- Ketonization, One-Pot Synthesis of Imidazo[1,2-a]benzimidazole and 1H-pyrrol-1-yl-1H-benzo[d]imidazole-5-carboxylate

應用化學系碩博士班

有氧環境、一鍋化、環化、酮基化、Aerobic Oxidative、One-Pot、Carbocyclization、Ketonization

(I) Multicomponent Synthesis of Functionalized Tetrahydroacridinones: New Insights into A Mechanistic Route (II) Synthesis of chemical probes and explore their application in new drug design (III) Synthesis of new chemical entities for Alzheimer's disease therapeutics

應用化學系碩博士班

活性標示探針、阿茲海默症、多組分反應、量子點、Michael adduct、Knoevenagel adduct、three-component、probes、Alzheimer's、Quantum dots、Tetrahydroacridinones

Synthesis Small Molecular Contain Sulfur、Selenium Heterocycle Biologic Compounds by One-pot under Ultrasonication and Synthesis Antrodia Cinnamomea of Mycelium AnaloguesSynthesis Small Molecular Contain Sulfur、Selenium Heterocycle Biologic Compounds by One-pot under Ultrasonication and Synthesis Antrodia Cinnamomea of Mycelium Analogues

應用化學系碩博士班

超音波、牛樟芝、藥物合成、一鍋化、異硒氰酸酯、雜環藥物、one-pot、ultrsonication、Antrodia Cinnamomea、Drug Synthesis、2-iminoselenazole、2-iminothiazole

Design and Synthesis of Heterocyclic Small Molecules of Biological Interest

應用化學系碩博士班

多樣性合成、伊博格鹼、乙內醯脲、氮雜䓬[4、5-b]吲哚、藥物開發、雜環、皮克特-施彭格勒類反應、特殊結構、設計合成、Diversity oriented synthesis、Iboga class alkaloid、Hydantoins、azepino[4、5-b]indoles、Drug discovery、Heterocycles、Pictet–Spengler-type reactions、Privileged structures、Synthesis design

Synthesis of Anticacer Bis (benzimidazoles) Library and Benzimidazolyl benzoxazole Related to UK-1

應用化學系碩博士班

組合化學、微波合成技術、Bis(benzimidazoles)分子庫、Combinationary chemistry、microwave、Bis(benzimidazoles)

Design and Synthesis of Diverse Pyrimidopyrroloquinoxalinediones,Metal-Assisted Synthesis of Benzimidazoles Molecular Library

應用化學系碩博士班

苯併咪唑、金屬催化、pyrimidopyrroloquinoxalinediones、Pictet-Spengler reaction

Palladium and Ruthenium Metal Catalytic Synthesis, and Synthesis of Sulfur and Selenium Heterocyclic Molecule Library

應用化學系碩博士班

分子庫、微波、有機金屬催化、Molecule Library、Palladium and Ruthenium Metal Catalytic Synthesi

Design and Synthesis of Quinazolines Derivatives from Amino Acid Esters ; Copper-Catalysed Aerobic Oxidative Carbocyclization- Ketonization , Synthesis of Imidazo[1,2-a]benzimidazole Derivatives

應用化學系碩博士班

喹唑啉衍生物、胺基酸酯、D-胺基酸氧化酶、銅催化、咪唑併[1、2-a]苯併咪唑衍生物、碳氫鍵活化、Quinazolines、Amino Acid Esters、D-Amino acid oxidase、Copper-Catalysed、Imidazo[1、2-a]benzimidazole、C-H Activation

One-Pot Domino Transformations Towards the Synthesis of Skeletally Diverse Heterocyclic Small Molecules

應用化學系碩博士班

一锅反应、多米诺转换、杂环、One-pot reaction、Domino transformations、Heterocycles

Study and Development of Drug Discovery and Medicine Synthesis and New Synthesis Methodology

應用化學系碩博士班

標靶藥物、類藥性分子庫、免疫抑制、超音波輔助、碳氫鍵活化、西羅多辛、Target-drug、Druglikeness、Immuno-suppressive、Ultrasound-assisted、C-H activation、Silodosin

Based on Lead Compound to Design and Synthesis of Heterocyclic Molecule Library,Metal-Assisted Synthesis and Diversification of Benzimidazoles

應用化學系碩博士班

雜環分子、苯并咪唑、三環咪唑內醯胺、離子液體、Heterocyclic molecule、Bezimidazole、Tricyclicimidazole lactam、Ion liquid

Ruthenium and Palladium catalytic Synthesis, and Diversification of Heterocyclic Small Molecule Library

應用化學系碩博士班

微波、離子液體、金屬催化、mirrowave、ion liquid、metal catalytic

Efficient Microwave-Enhanced Synthesis of Isoquinolinones and Quinoxalinediones Derivatives

應用化學系碩博士班

微波加熱、離子液體、多分子反應、基於片斷藥物設計、異氰多分子反應、皮克特-施彭格勒反應、microwave、ionic liquid、multicomponent reaction、fragmemt-based drug design、isocyanide-based multicomponent reaction、Pictet-Spengler reaction

Discovery of Novel RAD 51 and NF-kB Inhibitors : IBR2 Analogues and Aminofuran fused Benzimidazole and Synthesis of Phosphonyl Pyrazole fused Benzimidazole

應用化學系碩博士班

苯并咪唑、IBR2衍生物、NF-kB抑制劑、Benzimidazole、IBR2 analogues、NF-kB Inhibitors

Design and Synthesis of Small Organic Molecule via 2-cyanomethylbenzimidazole Compounds

應用化學系碩博士班

2 - 氰甲基苯并咪唑、有機小分子、2-cyanomethylbenzimidazole、Small Organic Molecule

Design, Synthesis, and Diversification of Heterocyclic Small Molecule Library

應用化學系碩博士班

癌症、微波、離子液體、Cancer、Microwave、Ionic liquid