李光申
Oscar Kuang-Sheng Lee・醫學院・臨床醫學研究所、生技醫療經營管理碩士在職學位學程
碩士平均畢業時長
2.46 年
中位數 2.44 年・5 人
在職專班平均畢業時長
2.54 年
中位數 2.00 年・7 人
博士平均畢業時長
7.24 年
中位數 6.07 年・17 人
收錄論文
56 篇
100–113 學年度
全校中位數(供對照)
碩士 2.10・在職專班 2.08・博士 6.11 年
畢業時長趨勢
每學年度畢業人數
只計入有論文收錄的畢業生;中途休學或更換指導教授的學生不會出現在這裡。
研究關鍵字
間葉幹細胞mesenchymal stem cellsmesenchymal stem cellosteogenic differentiation成骨分化Mesenchymal stromal cellsHepatic differentiation肝細胞分化間質幹細胞NoneRaman spectroscopymicrofluidic device骨分化幹細胞間葉系幹細胞外泌體exosomes癌症幹細胞mesenchymal stromal cellartificial intelligence老化硬度拉曼光譜儀osteogenesis拉曼光譜骨鈣素osteocalcin小腦萎縮症Spinocerebellar ataxiastem cellbreast cancer阿茲海默症tau蛋白神經發炎誘導性多能幹細胞iPSC衍生的外泌體Alzheimer's diseasetauneuroinflammationinduced pluripotent stem celliPSC-derived exosomes癌症相關成纖維細胞基質細胞衍生因子-1C-X-C 基序趨化因子受體 4腫瘤微環境Cancer-associated fibroblasts (CAFs)Stromal-derived factor-1 (SDF-1)C-X-C motif chemokine receptor 4 (CXCR4)Tumor microenvironment (TME)Cancer stem cells (CSCs)
想看最新的研究方向與計畫經費,也可以查政府研究計畫(GRB)。
指導論文
| 學年度 | 論文 | 學制 | 入學 | 提交日期 | 畢業時長 |
|---|---|---|---|---|---|
| 113 | Development of iPSC-Derived Exosomes as Therapeutics for Alzheimer’s Disease 臨床醫學研究所・共同指導:楊智宇 阿茲海默症、tau蛋白、神經發炎、誘導性多能幹細胞、外泌體、iPSC衍生的外泌體、Alzheimer's disease、tau、neuroinflammation、induced pluripotent stem cell、exosomes、iPSC-derived exosomes | 碩士 | 111 | 2025-01-10 | 2.44 年 |
| 113 | Cancer-Associated-Fibroblast-Mediated Paracrine and Autocrine SDF-1/CXCR4 Signaling Promotes Stemness and Aggressiveness of Colorectal Cancers 臨床醫學研究所 癌症相關成纖維細胞、基質細胞衍生因子-1、C-X-C 基序趨化因子受體 4、腫瘤微環境、癌症幹細胞、Cancer-associated fibroblasts (CAFs)、Stromal-derived factor-1 (SDF-1)、C-X-C motif chemokine receptor 4 (CXCR4)、Tumor microenvironment (TME)、Cancer stem cells (CSCs) | 博士 | 101 | 2024-11-23 | 12.31 年 |
| 113 | Post-operative Adjuvant Therapy Accelerates Recovery and Promotes Cartilage Regeneration Following High Tibial Osteotomy: A Retrospective Study 臨床醫學研究所 高位脛骨截骨手術、軟骨再生、改善患者膝關節的疼痛、再生醫學、臨床成效追蹤、高濃度血小板血漿、生物活性分子、關節鏡、HTO、PRP、High Tibial Osteotomy、Platelet-Rich Plasma、BaM、VAS、OKS、WOMAC、ICRS、Bio-active Molecules、Visual Analogue Scale、Oxford Knee Score、International Cartilage Repair Society | 博士 | 106 | 2024-06-05 | 6.84 年 |
| 112 | Development of Exosomes from Mesenchymal Stromal Cells as Therapeutics for Acute Lung Injury 轉譯醫學博士學位學程 急性肺部損傷、間質幹細胞、巨噬細胞、外泌體、微小核糖核酸、miR-7704、MyD88、STAT1、M2巨噬細胞、IFN𝛾/TNF-stimulated MSCs、mesenchymal stromal cell、exosome、macrophage polarization、Acute Lung Injury | 逕讀博士 | 104 | 2024-12-29 | 9.41 年 |
| 112 | Precision Identification of Locally Advanced Rectal Cancer in Denoised CT Scans Using EfficientNet and Voting System Algorithms 臨床醫學研究所・共同指導:楊智宇 直腸癌、局部晚期直腸癌、周邊切除邊緣、電腦斷層掃描、醫學影像處理、人工智慧、rectal cancer、local advanced rectal cancer、circumferential resection margin、computed tomography、medical image processing、artificial intelligence | 博士 | 107 | 2024-07-04 | 5.92 年 |
| 112 | Identification of pathways and biomarkers of frailty using artificial intelligence approaches 臨床醫學研究所 老化、衰弱症、衰弱指標、基因體、英國生物資料庫、Ageing、Frailty、Frailty index、genetics、UK Biobank | 碩士 | 110 | 2024-04-26 | 2.74 年 |
| 112 | Mesenchymal stem cells ameliorate acute liver failure in a porcine model and the potential role in liver transplant recipients 臨床醫學研究所・共同指導:蔡昕霖 急性肝衰竭、缺氧再灌注傷害、肝臟移植、間葉幹細胞、活性氧化物、acute liver failure、ischemia-reperfusion injury、liver transplantation、mesenchymal stem cell、reactive oxygen species | 博士 | 105 | 2023-11-23 | 7.31 年 |
| 111 | Application of Deep Learning Technique in Glaucoma Screening, Classification, and Pterygium Recurrence Prediction 臨床醫學研究所 高眼壓性青光眼、低眼壓性青光眼、眼翳、機器學習、復發、預測、分類、glaucoma、pterygium、classification、prediction、recurrence | 博士 | 101 | 2023-05-14 | 10.78 年 |
| 110 | The business trend analysis of primary clinics in Taipei under the impact of COVID-19 pandemic 生技醫療經營管理碩士在職學位學程・共同指導:鍾惠民 診所疫情受創、診所經營、診所經營趨勢、診所營運模式、全民健保、primary clinics、clinics business trends、primary clinics operating model、the COVID-19 pandemic、Taiwanese National Health Insurance | 碩士在職專班 | 109 | 2022-08-12 | 2.03 年 |
| 110 | Key Success Factors for Digital Transformation into a Smart Hospital-Mayo Clinic as an Example 生技醫療經營管理碩士在職學位學程 嚴重特殊傳染性肺炎、數位轉型、關鍵成功因素、梅約診所醫療體系、智慧醫院、社群媒體、coronavirus disease 2019 (COVID-19)、digital transformation、key success factors、Mayo Clinic、smart hospital、social media | 碩士在職專班 | 106 | 2022-08-03 | 5.00 年 |
| 110 | The System Design of Smart Pet Food Sharing Device 生技醫療經營管理碩士在職學位學程 寵物餵食器、排程餵食方法、系統設計、專利評估、Pet Feeder、Scheduled Feeding Method、System Design、Patent Evaluation | 碩士在職專班 | 109 | 2022-08-01 | 2.00 年 |
| 110 | The research of strategy of transformation and innovation in the electronics industry - A Dell Incorporation Case Study 生技醫療經營管理碩士在職學位學程 企業創新、企業轉型、轉型策略、藍海策略、持續性競爭優勢、Enterprise innovation、Enterprise transformation、Transformation strategy、blue ocean strategy、Sustainable competitive advantage | 碩士在職專班 | 109 | 2022-07-24 | 1.98 年 |
| 109 | Deep Learning Application for Vocal Fold Disease Prediction Through Voice Recognition 臨床醫學研究所 None、artificial intelligence、convolutional neural network、dysphonia、pathological voice、vocal fold disease、voice pathology identification | 博士 | 105 | 2021-09-04 | 5.09 年 |
| 109 | The development strategy and operation model of regional medical aesthetic clinics - A Clinic Case Study 生技醫療經營管理碩士在職學位學程 整形醫美診所、自費醫療、區域性經營模式、經營團隊、品牌、口碑、Plastic surgery clinics、self-funded medical care、regional business model、management team、brand、word of mouth | 碩士在職專班 | 108 | 2021-06-26 | 1.90 年 |
| 109 | Research on the Strategy of Taiwan's Biotechnology and Medical Industry Expansion to ASEAN Countries - a company case study 生技醫療經營管理碩士在職學位學程 南向、新南向、東協、兆元產業、生技醫療產業、Southbound、New Southbound、ASEAN、Trillion Industry、Biotech Medical Industry | 碩士在職專班 | 108 | 2021-06-23 | 1.89 年 |
| 108 | Role of Tissue Rigidity in the Differentiation of Human Pluripotent Stem Cells 臨床醫學研究所 多能性幹細胞、組織機械力學、硬度、長鏈非編碼RNA、內胚層分化、Pluripotent stem cells、Tissue mechanics、Rigidity、Long non-coding RNAs、Endoderm differentiation | 博士 | 104 | 2019-10-29 | 4.24 年 |
| 108 | Studies on the Mechanism of Bone Marrow Concentrate-Induced Mesenchymal Stem Cell Conditioned Medium Facilitates Wound Healing and Prevents Hypertrophic Scar Formation 臨床醫學研究所 骨髓濃縮液、間葉幹細胞、條件培養基、肥厚性疤痕、Bone marrow concentrate、Mesenchymal stem cell、Conditioned medium、Hypertrophic scar | 博士 | 105 | — | 無法計算 |
| 107 | Mechanical stretch induces hair regeneration through the alternative activation of macrophages 臨床醫學研究所・共同指導:陳志強 落髮、毛囊幹細胞、機械拉伸、再生、張力、alopecia、hair stem cells、mechanical stretch、regeneration、strain | 博士 | 101 | — | 無法計算 |
| 106 | Detection of live mesenchymal stem cells and their application in the treatment of arsenite induced peripheral vasculopathy 臨床醫學研究所 間葉幹細胞、拉曼光譜儀、砷、周邊血管病變、mesenchymal stem cells、Raman spectroscopy、Arsenite、Peripheral vascular diseases | 博士 | 97 | 2018-08-20 | 10.05 年 |
| 106 | Study on the Management Strategies of Orthopaedic Device Company – Case Analysis on a Taiwanese Company 生技醫療經營管理碩士在職學位學程 脊椎醫療器材、經營策略分析、骨科器材、Spine Medical Devices、Business Strategy Analysis、Orthopedic Devices | 碩士在職專班 | 104 | 2018-08-01 | 3.00 年 |
| 106 | The Study of Glycoscience and Tumor Metastasis in Gynecologic Cancer : from Bench to Clinic 臨床醫學研究所・共同指導:吳成文 婦產科癌症、子宮內膜癌、卵巢癌、EpCAM、EGFR、ST3Gal I、腫瘤移行、遠處轉移、gynecologic malignancies、endometrial cancer、ovarian cancer、tumor invasion、distant metastasis | 博士 | 98 | 2018-06-11 | 8.86 年 |
| 106 | Osteogenic Differentiation of Human Mesenchymal Stem Cells is Modulated by Stereo-topographical Cues and Time-dependent Stimulation of Parathyroid Hormone 臨床醫學研究所 間葉幹細胞、矽納米線、成骨分化、副甲狀腺素、蛋白激酶C、mesenchymal stem cells、silicon nanowires、osteogenesis、parathyroid hormone、protein kinase C | 博士 | 97 | — | 無法計算 |
| 105 | Endothelial Angiogenesis is Directed by RUNX1T1-mediated Secretome 微生物及免疫學研究所・共同指導:王學偉 內皮前驅細胞、血管生成、系統生物學、Endothelial progenitor cells、Angiogenesis、System biology | 博士 | 100 | 2017-08-23 | 6.06 年 |
| 105 | Exploration of lineage reversibility in mesenchymal stem cells and hepatocytes 分子醫學博士學位學程 間葉幹細胞、肝臟分化、可逆性、脫氧核糖核酸甲基轉移酶、乙型轉化生長因子、MSCs、Hepatic differentiation、Reversibility、Dnmt、TGFb1 | 博士 | 100 | 2017-05-23 | 5.81 年 |
| 105 | Detection of Hepatic Maturation in Mesenchymal Stromal Cells Undergoing Hepatic Differentiation and Hepatocyte De-differentiation by Raman Spectroscopy 生醫光電研究所 拉曼光譜、間充質基質細胞、肝臟細胞分化、肝細胞逆分化、外吐小體、Raman spectra、Mesenchymal stromal cells、Hepatic differentiation、Hepatocyte de-differentiation、Exosomes | 博士 | 100 | 2017-05-12 | 5.78 年 |
| 105 | Regulation of Genes Expression by Fluid-Induced Shear Stress in Bio-Microfluidic Device and Modulation of Proliferation with Different Growth Factors in Human Annulus Fibrosus Cells 臨床醫學研究所 椎間盤退化、纖維環細胞、剪力、維流體裝置、生長激、disc degeneration、annulus fibrosus cell、shear stress、microfluidic device、growth factor | 博士 | 97 | — | 無法計算 |
| 105 | Characterization of molecular mechanism regulating bone mineralization during osteogenic differentiation of mesenchymal stem cells 臨床醫學研究所 間葉幹細胞、骨鈣素、骨分化、礦化、拉曼光譜儀、鎂轉運體、mesenchymal stem cells、osteocalcin、osteogenic differentiation、mineralization、Raman spectroscopy、magnesium transporter | 博士 | 98 | — | 無法計算 |
| 105 | The Role of Dexamethasone on the Osteogenic Differentiation of Mesenchymal Stromal Cells ( MSCs) 生化暨分子生物研究所 糖皮質激素、組蛋白去乙醯酶6、間葉幹細胞、成骨分化、glucocorticoid receptor、hdac6、mesenchymal stem cell、osteogenic differentiation | 博士 | 97 | — | 無法計算 |
| 104 | Extraction of Ginkgo biloba Leaf Promotes Osteogenic Differentiation of Mesenchymal Stromal Cells 臨床醫學研究所 間葉幹細胞、銀杏葉、成骨分化、Mesenchymal stromal cells、Ginkgo biloba Leaf、Osteogenic differentiation | 碩士 | 103 | — | 無法計算 |
| 104 | Real-Time Detection of Benzoylecgonine by Using the Portable Surface Plasmon Resonance System 生醫光電研究所 表面電漿共振儀器、古柯鹼代謝物、可攜式儀器、即時檢測、Surface plasmon resonance、Benzoylecgonine、Portable system、Real-time detection | 碩士 | 102 | — | 無法計算 |
| 104 | Evaluation of neuroprotection effects from mesenchymal stem cells for the treatment of Spinocerebellar ataxia 臨床醫學研究所 小腦萎縮症、幹細胞、Spinocerebellar ataxia、stem cell | 碩士 | 103 | — | 無法計算 |
| 104 | Pre-clinical Evaluation of Therapeutic Efficacy of Human Mesenchymal Stromal Cells on Amyotrophic Lateral Sclerosis 臨床醫學研究所 幹細胞、間葉幹細胞、肌萎縮性脊髓側索硬化症、stem cell、mesenchymal stem cell、Amyotrophic lateral sclerosis、ALS | 碩士 | 103 | — | 無法計算 |
| 104 | Effects of matrix dimensionality and stiffness on osteogenic differentiation of mesenchymal stromal cells 分子醫學博士學位學程 間葉幹細胞、成骨分化、基質硬度、聚丙烯醯胺支架、mesenchymal stromal cells、osteogenesis、matrix stiffness、polyacrylamide scaffold | 博士 | 99 | — | 無法計算 |
| 104 | Effects of Three-dimensional Spherical Spatial Boundary Conditions on Osteogenic Differentiation of Mesenchymal Stromal Cells 分子醫學博士學位學程 三維支架、空間邊界、間葉幹細胞、骨分化、細胞骨架、focal adhesion、integrin、foam scaffold、spatial boundary condition (SBC)、mesenchymal stromal cell (MSC)、osteogenic differentiation、cytoskeleton | 博士 | 99 | — | 無法計算 |
| 103 | Elucidation of Molecular Mechanisms of Differential Mineralized Matrix Production during Osteogenic Maturation in Human Mesenchymal Stromal Cells 生醫光電研究所 間葉幹細胞、拉曼光譜、骨鈣素、Mesenchymal stromal cells、Raman spectroscopy、Osteocalcin | 碩士 | 101 | — | 無法計算 |
| 103 | Establishment of Disease-Specific Human Induced Pluripotent Stem Cells 臨床醫學研究所 誘導式多能性幹細胞、疾病模式、iPSC、disease model | 碩士 | 102 | — | 無法計算 |
| 103 | Rapid Generation of Hepatocyte-Like Cells from Mesenchymal Stromal Cells by a Fluid Shear Stress 生醫光電研究所 間葉幹細胞、流體剪應力、mesenchymal stromal cell、fluid shear stress | 碩士 | 102 | — | 無法計算 |
| 102 | Effects of Magnesium on Osteogenic Differentiation of Mesenchymal Stem Cells 生物醫學工程學系・共同指導:羅俊民 鎂離子、間葉幹細胞、成骨分化、Magnesium、Mesenchymal Stem Cells、Osteogenic Differentiation | 碩士 | 100 | 2014-08-27 | 3.07 年 |
| 102 | Study on the Combined Transplantation of Mesenchymal Stem Cell and Liver Sinusoidal Endothelial Cell to Promote Liver Regeneration 臨床醫學研究所 間葉幹細胞、肝竇內皮細胞、肝臟再生、Mesenchymal Stem Cell、Liver Sinusoidal Endothelial Cell、Liver Regeneration | 碩士 | 101 | 2014-08-25 | 2.06 年 |
| 102 | Multi-layered Environmental Regulation of Stem Cell Activation and Aging 老化、幹細胞、環境調控、免疫系統、群聚感應、aging、stem cells、environmental regulation、immune system、quorum sensing | 博士 | 94 | 2014-05-28 | 8.82 年 |
| 102 | Development of biophotonic tools for investigating the effects of chemical and mechanical factors in mesenchymal stem cells 臨床醫學研究所 表面電漿共振、間葉系幹細胞、RNA微-155、介白素-10、介白素-8、人類支氣管表皮細胞、Surface Plasmon Resonance (SPR)、Human mesenchymal stem cells (hMSCs)、microRNA-155、miR-155、Interleukin-10、IL-10、Interleukin-8、IL-8、human bronchial epithelial cells (hBECs) | 逕讀博士 | 97 | — | 無法計算 |
| 102 | Tissue Engineering of Functional Hepatic-like Tissues from Acellular Liver Scaffolds and Mesenchymal Stem Cells 生物醫學工程學系・共同指導:張寅 間葉幹細胞、去細胞肝臟支架、類肝臟組織、mesenchymal stem cells、acellular liver scaffolds、hepatic-like tissues | 博士 | 98 | — | 無法計算 |
| 101 | Study of CD133-expressing thyroid cancer stem cells in I-131 therapy and tumor initiating ability modulated by mesenchymal stromal cells 臨床醫學研究所・共同指導:劉仁賢 甲狀腺癌、CD133、癌症幹細胞、放射治療、碘131、間葉幹細胞、乳癌、綠色螢光蛋白、紅色螢光蛋白、活體螢光影像、螢光標誌細胞、Thyroid cancer、Cancer stem cell、Radiotherapy、I-131、Mesenchymal stromal cells、breast cancer、GFP、RFP、in vivo fluorescence imaging、fluorescent color-coded cells | 博士 | 96 | 2013-08-26 | 6.07 年 |
| 101 | Measurement of Young's Modulus Alteration during Osteogenic Differentiation in Human Mesenchymal Stem Cells by Atomic Force Microscopy 生醫光電研究所 間葉幹細胞、成骨分化、楊氏係數、原子力顯微鏡、硬度、Mesenchymal Stem Cells、Osteogenic differentiation、Young's modulus、Atomic Force Microscopy、Stiffness | 碩士 | 100 | 2013-07-25 | 1.98 年 |
| 101 | Study on the effects of hypoxia on human mesenchymal stem cells and their interaction with tumor cells 臨床醫學研究所 間葉幹細胞、乳癌細胞、低氧環境、Mesenchymal stem cell、Hypoxia、breast cancer | 博士 | 96 | — | 無法計算 |
| 101 | Translational Application in Regenerative Medicine: Using Mesenchymal Stem Cells for Acute Paraquat Poisoning and Donor-Specific Antibodies Associated Acute Rejection in Small Bowel and Multivisceral Transplantation 臨床醫學研究所 間葉型幹細胞、巴拉刈、氧化壓力、肺部傷害、抗捐贈者HLA的特異性抗體、急性排斥、小腸移植、多重器官移植、mesenchymal stem cells、paraquat、oxidative stress、pulmonary injury、donor-specific antibody、acute rejection、small bowel transplantation、multivisceral transplantation | 博士 | 93 | — | 無法計算 |
| 101 | Rapid Generation of Mature Hepatocyte-Like Cells from Mesenchymal Stem Cells by a Bio-Microfluidic Device 臨床醫學研究所 間葉幹細胞、微流體裝置、肝細胞分化、肝細胞、Mesenchymal stem cells、Microfluidic device、Hepatic differentiation、Hepatocytes | 碩士 | 100 | — | 無法計算 |
| 101 | Rapid Generation of Mature Hepatocyte-Like Cells from Human Induced Pluripotent Stem Cells by a Microfluidic Device 生物醫學工程學系・共同指導:羅俊民 誘導性多功能幹細胞、肝細胞分化、類肝細胞、微流體系統、induced pluripotent stem cells (iPSCs)、hepatic differentiation、hepatocyte-like cells、microfluidic device | 碩士 | 100 | — | 無法計算 |
| 100 | Effects of glucose reduction on human mesenchymal stem cell and its phosphoproteomic changes during osteogenic differentiation 臨床醫學研究所 間質幹細胞、低糖、粒線體、骨分化、磷酸化蛋白體、mesenchymal stem cell、glucose、mirochondria、osteogenic differentiation、phosphoproteomics | 博士 | 95 | 2011-12-06 | 5.35 年 |
| 100 | Study of immuno-mechanism in graft-versus-host disease and its treatment with mesenchymal stem cells 臨床醫學研究所 造血幹細胞、樹突細胞、間葉系幹細胞、協助型T細胞、細胞激素、移植體對宿主反應疾病、Hematopoietic Stem Cell、Dendritic Cell、Mesenchymal Stem Cell、T Helper Cell、Cytokine、Graft-versus-Host Disease | 博士 | 96 | 2011-11-17 | 4.30 年 |
| 100 | Mesenchymal stem cell therapy for renal disease 臨床醫學研究所 免疫調節、狼瘡腎炎、臍帶血、間質幹細胞、慢性腎臟疾病、上皮間質轉分化、肝細胞生長因子、骨髓、Immunomodulation、lupus nephritis、umbilical cord blood、mesenchymal stem cells、chronic kidney disease、epithelial to mesenchymal transition、hepatocyte growth factor、bone marrow | 博士 | 93 | — | 無法計算 |
| 100 | The role of miR-101 during Hepatogenic Differentiation of Human Mesenchymal Stromal Cells 臨床醫學研究所 間葉系基質細胞、肝細胞分化、miR-101 | 碩士 | 97 | — | 無法計算 |
| 100 | Real-time Detection of Osteogenic Maturation in Mesenchymal Stromal Cells by Raman Spectroscopy 生醫光電研究所 None | 碩士 | 99 | — | 無法計算 |
| 100 | Mesenchymal stem cells: therapeutic effects on mouse model of spinocerebellar ataxia and the effects of superparamagnetic iron oxide nanoparticles labeling 臨床醫學研究所 間葉幹細胞、細胞移植、小腦萎縮症、超順磁氧化鐵、奈米粒子、多品系分化能力、mesenchymal stem cells、cell transplantation、spinocerebellar ataxia、superparamagnetic iron oxide、nanoparticles、multilineage differentiation | 博士 | 93 | — | 無法計算 |
| 100 | Exploring the roles of microRNA-503 in hepatogenic differentiation of mesenchymal stem cells 臨床醫學研究所 間葉系幹細胞、微型核醣核酸、肝細胞分化、mesenchymal stem cells、micro RNA、hepatogenic differentiation | 碩士 | 98 | — | 無法計算 |
| 100 | Effects of Rac1 Inhibition on Hepatic Differentiation of Mesenchymal Stromal Cells 臨床醫學研究所 None | 碩士 | 99 | — | 無法計算 |